Implantable fibrous membranes such as resorbable membranes, can act as scaffolds, supporting tissue following trauma or surgical procedures. These applications require highly biocompatible and bio-absorbable materials. Implantable membranes, woven or non-woven, can be prepared from gelatin, among other options, using electrospinning to provide a favorable cell growth scaffold. However, the presence of endotoxins in gelatins pose negatively impacts safety in this application.
Residual endotoxins, a common cause of complications in surgical applications
Residual endotoxins are a common cause of complications in surgical applications. In the United States alone, 40,000 out of 500,000 annual arthroplasties require revisions due to aseptic loosening – a problem often associated with the presence of endotoxins (Goveia, et al., 2016).
Improving implantable membrane safety with X-Pure®
X-Pure’s low-endotoxin gelatins and collagens provide the highest possible purity and safety profile and can therefore significantly improve safety in the field of implantable membranes.