Implantable membranes

Implantable fibrous membranes can act as scaffolds to support tissue following trauma or surgical procedures, but should be made from ultra-pure, highly biocompatible, and bio-absorbable materials.

Surgical recovery can be complicated by endotoxins

Residual endotoxins can be a common cause of complications in surgical application. In the United States alone, 40,000 out of 500,000 annual arthroplasties require revisions due to aseptic loosening – a problem often associated with the presence of endotoxins. ^[1]

Weaving a safe implantable mesh

Gelatins can be spun using a technique known as electrospinning. Using this technique, we can create woven or non-woven implantable membranes to serve as favorable cell growth scaffolds using X-Pure®'s ultra-low endotoxin, highly biocompatible, and bio-absorbable gelatins. Gelatin fibrous membranes have been demonstrated as a promising scaffold for bone marrow stromal cells^[2].

References:

[1] Goveia VR, Mendoza IYQ, Guimarães GL, Ercole FF, Couto BRGM, Leite EMM, et al. Endotoxins in surgical instruments of hip arthroplasty. Rev Esc Enferm USP. 2016;50(3):405-410

[2] Zhang, Y., Ouyang, H., Lim, C.T., Ramakrishna, S. and Huang, Z.M., 2005. Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds. Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials, 72(1), pp.156-165