Because of the increase in surgery, the hemostatic market is growing rapidly, with an expected Compound Annual Growth Rate (CAGR) of 6.2% a year from 2015 to 2020(4). At the same time, surgeons need better hemostatic agents to reduce the number of deaths from hemorrhaging during surgery.
X-Pure®: a new standard in hemostatic applications
Major trauma due to bleeding leads to as many as five million deaths each year. Severe bleeding accounts for about 80% of deaths in the operating theatre (Gaunt and Woolley, 2014). Gelatin can be designed to absorb more than 40 times its own weight and is widely accepted as an ideal material to control blood flow through hemostatic applications, mainly in the form of sponges, strips, powder or nanofibers. In the majority of these products, acid porcine skin gelatins are used, because of their greater stability and better foaming properties. For a few specific purposes, lime bovine bone gelatins are preferred. However, endotoxins in hemostatics can cause an exaggerated immune response and at high quantities, even septic shock (Opal, 2010).
Saving lives in surgery with high-purity hemostatics
Offering one of the lowest endotoxin acid porcine skin gelatin available on today’s market, Rousselot Biomedical’s X-Pure is an exceptionally safe gelatin solution for in-body hemostatic use. X-Pure consists of a comprehensive range of high-purity gelatins and collagens.
Advantages of X-Pure
X-Pure offers numerous benefits over alternative hemostatic agents:
- Endotoxin levels below 20 EU/g or even below LAL analysis detection limits if required
- The world's lowest levels for acid porcine skin gelatin, along with the outstanding foaming properties you can expect from this specific gelatin
- Excellent absorption capacity: gelatin absorbs at least 40 times its own weight of blood and can expand by 200%
- Biocompatible and biodegradable
- Fast acting, non-antigenic
- Easily grindable for syringe application, for instance, if you want to combine gelatin with thrombin
- Suitable for both human and veterinary hemostatic applications
- Generally Recognized As Safe (GRAS) by the USA's Food and Drug Administration (FDA) and compliant with the US, European and Japanese pharmacopeia